Carprofen is a non-steroidal anti-inflammatory (NSAID) medication that helps relieve the pain and inflammation that occurs with arthritis in dogs. It also helps bring relief from other joint problems and can help your pet to feel better after surgery. Carprofen is the generic alternative to Rimadyl, Novox, and Vetprofen.
For oral use in dogs only
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes
ibuprofen, naproxen, and ketoprofen.
Carprofen Caplets are indicated for the relief of pain and inflammation associated with osteoarthritis and for the
control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
DOSAGE AND ADMINISTRATION:
Always provide Client Information Sheet with prescription. Carefully consider the potential benefits and risk of
Carprofen Caplets and other treatment options before deciding to use Carprofen Caplets. Use the lowest
effective dose for the shortest duration consistent with individual response. The recommended dosage for oral
administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as
2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the
control of postoperative pain, administer approximately 2 hours before the procedure. Caplets are scored and
dosage should be calculated in half-caplet increments.
Carprofen Caplets should not be used in dogs exhibiting previous hypersensitivity to carprofen.
Keep out of reach of children. Not for human use. Consult a physician in cases of accidental ingestion by humans. For use in dogs only. Do not use in cats.
All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data prior to, and periodically during, administration of any NSAID should be considered. Owners should be advised to observe for signs of potential drug toxicity.
As a class, cyclooxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. Carprofen is an NSAID, and as with others in that class, adverse reactions may occur with its use. The most frequently reported effects have been gastrointestinal signs. Events involving suspected renal, hematologic, neurologic, dermatologic, and hepatic effects have also been reported. Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with renal, cardiovascular, and/or hepatic dysfunction. Concurrent administration of potentially nephrotoxic drugs should be approached cautiously, with appropriate monitoring. Concomitant use of Rimadyl with other anti-inflammatory drugs, such as other NSAIDs or corticosteroids, should be avoided because of the potential increase of adverse reactions, including gastrointestinal ulcerations and/or perforations. Sensitivity to drug-associated adverse reactions varies with the individual patient. Dogs that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Rimadyl treatment was not associated with renal toxicity or gastrointestinal ulceration in well-controlled safety studies of up to ten times the dose in healthy dogs.
Carprofen Caplets are not recommended for use in dogs with bleeding disorders (e.g., Von Willebrand’s disease), as safety has not been established in dogs with these disorders. The safe use of Rimadyl in animals less than 6 weeks of age, pregnant dogs, dogs used for breeding purposes, or in lactating bitches has not been established. Studies to determine the activity of Rimadyl when administered concomitantly with other protein-bound or similarly metabolized drugs have not been conducted. Drug compatibility should be monitored closely in patients requiring additional therapy. Such drugs commonly used include cardiac, anticonvulsant and behavioral medications. It has been suggested that treatment with carprofen may reduce the level of inhalant anesthetics needed.
INFORMATION FOR DOG OWNERS:
Carprofen, like other drugs of its class, is not free from adverse reactions. Owners should be advised of the potential for adverse reactions and be informed of the clinical signs associated with drug intolerance. Adverse reactions may include decreased appetite, vomiting, diarrhea, dark or tarry stools, increased water consumption, increased urination, pale gums due to anemia, yellowing of gums, skin or white of the eye due to jaundice, lethargy, incoordination, seizure, or behavioral changes. Serious adverse reactions associated with this drug class can occur without warning and in rare situations result in death. Owners should be advised to discontinue Rimadyl therapy and contact their veterinarian immediately if signs of intolerance are observed. The vast majority of patients with drug related adverse reactions have recovered when the signs are recognized, the drug is withdrawn, and veterinary care, if appropriate, is initiated. Owners should be advised of the importance of periodic follow up for all dogs during administration of any NSAID.
Store at controlled room temperature 15°-30°C (59°-86°F).