- VETERINARY PRESCRIPTION REQUIRED
- This drug is not approved for human use.
brand of amitraz liquid concentrate
For topical use on dogs
For Use In Animals Only
Mitaban is used to treats Mange caused by mites. Eliminating the mites responsible for the mange with Mitaban pet meds eases itching, skin irritation, and other symptoms, and helps prevent secondary infections associated with scratching and picking.
Toxicology studies conducted in the dog and other species suggest amitraz may alter the animal’s ability to maintain homeostasis. Animals treated with MITABAN (amitraz) should not be subjected to stress for a period of at least 24 hours posttreatment. Adverse reactions including three fatalities were reported during the clinical studies. In excess of 1100 patients with generalized demodicosis were topically treated with MITABAN.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
MITABAN Liquid Concentrate (amitraz) contains 19.9% N’-(2,4-dimethylphenyl)-N-[[2,4-dimethylphenyl) imino] methyl]-N-methyl-methanimidamide (w/w), and also xylol, propylene oxide, and a blend of alkyl benzene sulfonates and exthoxylated polyethers. Amitraz, a diamide, is pale yellow, has a melting point of 86° to 87° C, is not hygroscopic, is stable to heating, soluble in most organic solvents, and sparingly soluble in water.
MITABAN (amitraz) is indicated for treatment of generalized demodicosis (Demodex canis) in dogs. Current data do not support use for treatment of localized demodicosis or scabies.
DOSAGE AND ADMINISTRATION:
Long and medium-haired dogs should be clipped closely before treating. Prior to the initial treatment, all dogs should be bathed with a mild soap and water and towel dried. The entire animal should then be topically treated with MITABAN (amitraz) at a rate of 10.6 milliliters (contents of one bottle) per 2 gallons of warm water (250 ppm active drug). Two bottles (21.2 milliliters) per four gallons of water may be necessary to treat large dogs. The entire dog should be thoroughly and completely wetted with the mixture, and then allowed to air dry. Do not rinse or towel dry the dog after treatment with MITABAN. A fresh MITABAN-water mixture should be prepared for each patient; using the same mixture for more than one patient can spread other dermal infections and also the concentration of MITABAN could be reduced to a level which would be less effective than the recommended concentration.
Three to six topical treatments (14 days apart) are recommended for treatment of generalized demodicosis. It is important to continue the treatment until no viable (alive) mites are found in the skin scrapings at two successive treatments, or until six treatments have been applied. Severe (chronic) cases and dogs which are reinfested may require a second and third series of treatments, and again the treatment should be applied at 14 day intervals. Discontinue treatment of dogs which do not respond clinically.
When employing MITABAN for treatment of demodicosis, other dogs in the home also should be examined for lesions to ascertain whether treatment of these animals is warranted.
Though eye or dermal irritation was not reported during controlled experiments, such effects have been infrequently reported from clinical use. Consistent with good veterinary practice, it is recommended that a protectant be used in the eyes of patients prior to facial treatment with any topical therapy. Well-controlled experiments with MITABAN® (amitraz) have not been conducted to determine the compatibility range with other products.
Store at controlled room temperature 20° to 25°C (68° to 77°F)