Cerenia Injectable Solution 10 mg/mL, 20 mL contains maropitant citrate which acts an antiemetic to stop vomiting in dogs and cats. By blocking substance P, a compound responsible for triggering vomiting, Cerenia can actually prevent acute vomiting in dogs and cats. Does not cause sedation.
CERENIA® INJECTABLE SOLUTION (maropitant citrate)
Cerenia (maropitant citrate 10 mg/mL) Injectable Solution is indicated for the prevention and treatment of acute vomiting in dogs. It may be used interchangeably with Cerenia Tablets for once-daily dosing to prevent acute vomiting. Recommended for use in dogs 16 weeks and older.
DOSAGE AND ADMINISTRATION:
: Administer CERENIA Injectable Solution subcutaneously at 1 mg/kg
(0.45 mg/lb) equal to 1 mL/kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive days. Use of
refrigerated product may reduce the pain response associated with the injection.
CERENIA Injectable Solution is recommended for use in dogs 8 weeks and older and cats 16 weeks and older. >
For subcutaneous injection only. The safe use of CERENIA has not been evaluated in dogs
or cats used for breeding, or in pregnant or lactating bitches or queens. The safe use of CERENIA has not been
evaluated in dogs or cats with gastrointestinal obstruction, or dogs or cats that have ingested toxins.
Use with caution in patients with hepatic dysfunction because CERENIA is metabolized by CYP3A enzymes
(see Pharmacokinetics). Use with caution with other medications that are highly protein bound. The
concomitant use of CERENIA with other protein bound drugs has not been studied in dogs or cats. Commonly
used protein bound drugs include NSAIDs, cardiac, anticonvulsant, and behavioral medications. The influence
of concomitant drugs that may inhibit the metabolism of CERENIA has not been evaluated. Drug compatibility
should be monitored in patients requiring adjunctive therapy.
CERENIA causes dose related decreases in appetite and body weight. To maximize therapeutic potential of CERENIA, the underlying cause of vomiting should be identified and addressed in dogs receiving CERENIA.
Not for use in humans. Keep out of reach of children. In case of accidental ingestion, seek
medical advice. Topical exposure may elicit localized allergic skin reactions in some individuals. Repeated or
prolonged exposure may lead to skin sensitization. Wash hands with soap and water after administering drug.
CERENIA is also an ocular irritant. In case of accidental eye exposure, flush with water for 15 minutes and
seek medical attention.
In puppies younger than 11 weeks of age, histological evidence of bone marrow hypoplasia was seen at higher
frequency and greater severity in puppies treated with CERENIA than in control puppies. In puppies 16 weeks
and older, bone marrow hypoplasia was not seen.
CERENIA Injectable Solution should be stored at controlled room temperature
20-25°C (68-77°F) with excursions between 15-30°C (59-86°F). After first vial puncture, CERENIA Injectable
Solution should be stored at refrigerated temperature 2-8°C (36-46°F). Use within 90 days of first vial puncture.
Stopper may be punctured a maximum of 25 times.