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    Amlodipine Besylate 5mg

    Generic Equivalent To Norvasc

    Prescription RequiredAmlodipine Besylate 5mg
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    Product ID: *AMLOBESY5

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    Product Summary

    • FDA-Approved Amlodipine Besylate 5mg
    • Generic equivalent to Norvasc
    • See Instructions Below

    What is Amlodipine Besylate 5 mg?

    Amlodipine besylate is the besylate salt of amlodipine. Commonly used for treating hypertension and Coronary Artery Disease (CAD), it is a long-acting calcium channel blocker described chemically as 3-Ethyl-5-methyl. Its empirical formula is C20H25CIN2O5•C6H6O3S and here is an illustration of its structural formula:

    Amlodipine Besylate 5mg tablets are second generation calcium antagonists (slow-channel blocker or a calcium ion antagonist). It is also a peripheral arterial vasodilator which reduces peripheral vascular resistance and blood pressure. Their function is to deter or prevent the influx of calcium ions into cardiac muscles and vascular smooth muscle.

    The tablets are intended for oral administration. In addition, it has amlodipine besylate as an active ingredient. The inactive ingredients include microcrystalline cellulose, anhydrous, sodium starch glycolate, dibasic calcium phosphate, and magnesium stearate.

    What is Amlodipine Besylate 5mg Tablets Used for?

    Amlodipine Besylate 5 mg tablets are most commonly used for the following conditions:


    Sometimes referred to as high blood pressure, in this condition the blood pushes forcefully against the arterial walls. This may eventually cause heart problems.

    Amlodipine Besylate tablets are used in the treatment of hypertension, with a recommended minimum dosage of 5mg daily. They may be taken alone or in conjunction with other hypertension medication.

    Coronary Artery Disease (CAD)

    i. Chronic Stable Angina

    Chest discomfort caused when the heart is working hard and requires more oxygen. An example would be during exercise.

    Amlodipine besylate tablets are used to treat the symptoms of chronic stable angina. They may be taken alone or in conjunction with other antianginal agents.

    ii. Vasospastic Angina (Prinzmetal's or Variant Angina)

    Pain in Vasospastic Angina occurs when the person is at rest. These attacks usually happen between midnight and early morning and are quite painful.

    Amlodipine besylate tablets are used in cases of confirmed or suspected vasospastic angina. These tablets may be taken in conjunction with other antianginal agents or alone as prescribed by the primary physician.

    iii. Angiographically Documented CAD

    Amlodipine besylate tablets are used to reduce the likelihood of a coronary revascularization procedure or the risk of hospitalization due to angina. This particularly applies to those patients who have recently been exhibiting signs of CAD by angiography and haven't suffered from heart failure or an ejection fraction (less than 40%).

    Amlodipine Besylate 5mg Side Effects

    In clinical trials the following side effects were reported. These range from mild to moderate levels.

    The known side effects and warnings related to amlodipine besylate 5mg tablets include:

    • Caution must be taken, particularly by those patients with severe aortic stenosis as asymptomatic hypotension may occur. Due to the fact that vasodilation that results from amlodipine besylate tablets is gradual in onset, acute hypotension has rarely been reported after oral administration.
    • Angina conditions could worsen or acute myocardial infarction could develop when the tablets are initially taken. This could happen by increasing the dose as well, especially in patients with severe CAD.
    • Amlodipine is not a beta-blocker. As a result it gives no protection against the dangers of abrupt beta-blocker withdrawal. It is recommended that any withdrawal should be achieved by a gradual reduction of the dose.
    • Patients with severe hepatic impairment should exercise caution since amlodipine is extensively metabolized by the liver. Titration of the medication will be required; an initial low dosage could gradually be increased and monitored by your doctor.
    • The most common side effects that have been reported are headache and edema.

    As Amlodipine Besylate comes with a number of side effects, the recommendation is to strictly follow the doctor's instructions.

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