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    Felimazole 5 mg Tablets

    Felimazole 5 mg Tablets

    Product ID: *V**FELIMAZOLE50

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    Product Summary

    This product requires a valid prescription for shipment, please note that HealthWarehouse.com may not accept prescriptions faxed or emailed by patients.
    • VETERINARY PRESCRIPTION REQUIRED
    • This drug is not approved for human use.
    >

    Federal law restricts this drug to use by or on the order of a licensed veterinarian.


    Description:

    Hyperthyroidism, or overactive thyroid, in cats causes weight loss, increased appetite, excessive thirst, hair loss, and more. While there is no permanent treatment for hyperthyroidism, your veterinarian can help your cat feel better by regulating the thyroid with prescription Felimazole. The active ingredient in each small, coated pill is methimazole, which reduces the amount of the thyroid hormone your cat’s thyroid gland produces. The result is a healthier cat and a better quality of life.



    Warnings:

    Not for use in humans. Keep out of reach of children. For use in cats only. Wash hands with soap and water after administration to avoid exposure to drug. Do not break or crush tablets. Methimazole is a human teratogen and crosses the placenta concentrating in the foetal thyroid gland. There is also a high rate of transfer into breast milk. Pregnant women or women who may become pregnant, and nursing mothers should wear gloves when handling tablets, litter or bodily fluids of treated cats.

    Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.


    Indications:

    Methimazole is a thioureylene antithyroid drug, which inhibits the synthesis of thyroid hormones. Methimazole (1-methylimidazole-2-thiol) is a white, crystalline substance that is freely soluble in water. Indication: For the management of hyperthyroidism in cats.


    Caution:

    Do not use in cats with primary liver disease or renal failure. Do not use in cats with autoimmune disease. Do not use in cats with hematological disorders (such as anemia, neutropenia, lymphopenia, or thrombocytopenia) or coagulopathies. Do not use in breeding, pregnant or lactating cats. Laboratory studies in rats and mice have shown evidence of teratogenic and embryotoxic effects of methimazole. Cautions: Use of Felimazole in cats with renal dysfunction should be carefully evaluated. Reversal of hyperthyroidism may be associated with decreased glomerular filtration rate and a decline in renal function, unmasking the presence of underlying renal disease. Due to potentially serious adverse reactions such as hepatopathy, immune-mediated anemia, thrombocytopenia, and agranulocytosis, cats on methimazole therapy should be monitored closely for any sign of illness including fever, lymphadenopathy or signs of anemia. If a cat becomes ill while on Felimazole tablets, the drug should be stopped and appropriate hematological and biochemical testing should be done. Some hyperthyroid cats with concurrent diabetes mellitus treated with methimazole have decreases in their insulin requirements. It is recommended that the dose of insulin be reduced. Blood glucose, serum fructosamine, thyroid hormone concentrations and clinical signs of hypoglycemia should be closely monitored since the clinical course of the diabetes mellitus may be unpredictable.i The disposition of other drugs may change as hyperthyroid cats become euthyroid. The use of concomitant medications has not been fully evaluated in cats treated with methimazole. Methimazole does not address the underlying cause of feline hyperthyroidism.


    Dosage and Administration:

    The starting dose of Felimazole tablets is 2.5 mg administered orally every 12 hours. Following 3 weeks of treatment, the dose should be titrated based on total T4 (TT4) concentrations; the usual goal is to have TT4 within the normal range as well as a good clinical response. Dose adjustments should be made in 1.25 mg or 2.5 mg increments. The maximum total dosage is 15 mg per day divided, not to exceed 10 mg as a single administration. Hematology, biochemistry, and TT4 should be evaluated prior to initiating treatment and monitored after 3 weeks and 6 weeks of treatment. Thereafter, bloodwork should be monitored every 3 months and the dose adjusted as necessary. Cats receiving doses greater than 10 mg per day should be monitored more frequently.

    Storage and Use:

    Store between 15°C and 25°C. Keep the container tightly closed in order to protect from moisture. Methimazole is known to be sensitive to light. Protect the tablets from light if removed from the original container and not used immediately.


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