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    ApexiCon E 0.05% Cream- 60g

    Product ID: **APEXICONE60

    ApexiCon E 0.05% Cream- 60g

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    Product Summary

    This product requires a valid prescription for shipment, please note that HealthWarehouse.com may not accept prescriptions faxed or emailed by patients.

    PRESCRIPTION REQUIRED


    IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

    (dye FLOR a sone)

    COMMON BRAND NAME(S): ApexiCon E; Psorcon

    USES: For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.. If you are taking this medication for self-treatment, it is important to read the manufacturer\'s package instructions carefully so you know when to consult your doctor or pharmacist. (See also Precautions.)

    HOW TO USE: Apply the smallest amount that will cover affected area. For topical use only; avoid contact with eyes and mucous membranes. Do not apply to face or intertriginous areas. Do not use if there is atrophy at the treatment site. Minimize contact to nonaffected areas of the body. Wash hands after use.

    SIDE EFFECTS: All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: •Dry skin. •Itching. •Burning. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to your national health agency. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    PRECAUTIONS: Adrenal suppression May cause hypercortisolism or suppression of hypothalamic-pituitary-adrenal (HPA) axis, particularly in younger children or in patients receiving high doses for prolonged periods. HPA axis suppression may lead to adrenal crisis.Ref Systemic effects Topical corticosteroids may be absorbed percutaneously. Absorption of topical corticosteroids may cause manifestations of Cushing syndrome, hyperglycemia, or glycosuria. Absorption is increased by the use of occlusive dressings, application to denuded skin, or application to large surface areas.Ref Skin infections Use appropriate antibacterial or antifungal agents to treat concomitant skin infections; discontinue diflorasone if infection does not resolve promptly.Ref Contact dermatitis Allergic contact dermatitis can occur, it is usually diagnosed by failure to heal rather than clinical exacerbation.Ref Immunosuppression Prolonged use may result in fungal or bacterial superinfection; discontinue if dermatological infection persists despite appropriate antimicrobial therapy.Ref Kaposi sarcoma Prolonged treatment with corticosteroids has been associated with the development of Kaposi sarcoma (case reports); if noted, discontinuation of therapy should be considered.Ref Ocular effects Subcapsular cataracts, glaucoma (with possible nerve damage), and increased intraocular pressure have been reported with topical use.Ref Skin reactions Local adverse effects (eg, atrophy, striae, telangiectasias, burning, itching, irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, and miliaria) may occur. Reactions may not be reversible and may be more likely to occur with prolonged use, higher potency corticosteroids, and occlusive dressings.Ref Appropriate use For external use only; avoid contact with eyes and mucous membranes. Do not use with occlusive dressing unless using for psoriasis or recalcitrant conditions. Do not use on the face, axillae, or groin or for the treatment of rosacea or perioral dermatitis. Children may absorb proportionally larger amounts after topical application and may be more prone to systemic effects. HPA axis suppression, intracranial hypertension, and Cushing syndrome have been reported in children receiving topical corticosteroids. Prolonged use may affect growth velocity; growth should be routinely monitored in pediatric patients. Diflorasone is not FDA-approved for use in children. Topical corticosteroids are not recommended for extensive use, in large quantities, or for long periods of time in pregnant women. It is not known if diflorasone is excreted in breast milk following topical application; systemically administered corticosteroids are excreted in breast milk. The manufacturer recommends that caution be exercised when administering diflorasone to nursing women. If used during breastfeeding, do not apply on the chest to avoid accidental ingestion by the infant.

    DRUG INTERACTIONS: Aldesleukin- Corticosteroids may diminish the antineoplastic effect of Aldesleukin. Avoid combination. Corticorelin- Corticosteroids may diminish the therapeutic effect of Corticorelin. Specifically, the plasma ACTH response to corticorelin may be blunted by recent or current corticosteroid therapy. Monitor therapy. Deferasirox- Corticosteroids may enhance the adverse/toxic effect of Deferasirox. Specifically, the risk for GI ulceration/irritation or GI bleeding may be increased. Monitor therapy. Hyaluronidase- Corticosteroids may diminish the therapeutic effect of Hyaluronidase. Management: Patients receiving corticosteroids (particularly at larger doses) may not experience the desired clinical response to standard doses of hyaluronidase. Larger doses of hyaluronidase may be required. Consider therapy modification. Ritodrine- Corticosteroids may enhance the adverse/toxic effect of Ritodrine. Monitor therapy

    OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include mental/mood changes, slurred speech, difficulty awakening.

    NOTES: Do not share this medication with others. Lifestyle changes such as stress reduction programs, stopping smoking, limiting alcohol, and diet changes (e.g., avoiding caffeine and spicy foods) may increase the effectiveness of this medication. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Laboratory and/or medical tests may be performed to monitor your progress or check for side effects. Consult your doctor for more details.

    MISSED DOSE: Put on a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time.•Do not put on 2 doses at the same time or extra doses.

    STORAGE: Store at room temperature.Keep lid tightly closed.Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

    Information last revised October 2018. Copyright(c) 2018 First Databank, Inc.

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